Human noroviruses (huNoV) are the most frequent cause of non-bacterial acute gastroenteritis worldwide, particularly genogroup II genotype 4 (GII.4) variants.The viral nonstructural (NS) proteins encoded by the ORF1 polyprotein induce vesical clusters harboring the viral replication sites.Little is known so far about the ultrastructure of these rep
Gas explosions in coal mine gobs caused by the spontaneous combustion of coal usually result in serious threat to energy security.The main feature is that the explosion flame is initially disturbed by the coal gangue.To recognize the characteristics of gas explosion under 1073spx the continuous disturbance of gangue, based on the explosion accident
There is a large number of effective cytotoxic drugs whose side effect profile, efficacy, and long-term use in man are well understood and documented il barone wine over decades of use in clinical routine e.g.in the treatment of recurrent glioblastoma multiforme (GBM) and the hormone-refractory prostate cancer (HRPC).Both cancers are insensitive ag
Microbial cell individuality is receiving increasing interest in the scientific community.Individual cells within clonal populations exhibit noticeable phenotypic heterogeneity.The advent of fluorescent protein technology and advances in single-cell analysis has revealed phenotypic cell variant in bacterial populations.This heterogeneity is evident